Histologic similarities in children with eosinophilic esophagitis and proton pump inhibitor –responsive esophageal eosinophilia
Distinguishing between eosinophilic esophagitis (EoE), gastroesophageal reflux disease (GERD), and proton pump inhibitor (PPI)-responsive esophageal eosinophilia (PPI-REE) is difficult because symptoms overlap and there is no pathognomonic histologic feature for these disorders.1 Current EoE diagnostic guidelines define EoE as a clinicopathological condition characterized by symptoms of esophageal dysfunction and greater than 15 eosinophils per hpf (eos/hpf) in the esophageal mucosa after ruling out other etiologies as a cause of inflammation.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Nathalie Nguyen, Anna Baumgarten, Benjamin L. Wright, Kelley E. Capocelli, Zhaoxing Pan, James J. Lee, Glenn T. Furuta, Joanne C. Masterson Tags: Letter to the Editor Source Type: research
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