Bisretinoids mediate light sensitivity resulting in photoreceptor cell degeneration in mice lacking the receptor tyrosine kinase Mer [Metabolism]
In conclusion, the light sensitivity of photoreceptor cell degeneration arising from Mertk deficiency is consistent with the known phototoxicity of bisretinoids.
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Jin Zhao, Keiko Ueda, Marina Riera, Hye Jin Kim, Janet R. Sparrow Tags: Molecular Bases of Disease Source Type: research
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