An inborn error of innate immunity leading to severe rhinovirus infections

When a human population is exposed to a pathogenic virus, the outcomes among individuals may include asymptomatic, mild, severe, or no infection. Multiple parameters control these responses, including the amount of virus taken up, the age of the host, general health status, nutrition, and more. With the advent of whole exome sequencing we can now […]
Source: virology blog - Category: Virology Authors: Tags: Basic virology Information IFIH1 IFN inborn error innate immune sensor MDA5 missense respiratory infection rhinovirus viral viruses Source Type: blogs