ATF3 Confers Resistance to Pneumococcal Infection Through Positive Regulation of Cytokine Production

Conclusions. Taken together, we can conclude that ATF3 regulates innate immunity positively upon pneumococcus infection by enhancing TNF-α, IL-1β, and IFN- expression and modulating bacterial clearance.

Source: The Journal of Infectious Diseases - November 7, 2014 Category: Infectious Diseases Authors: Nguyen, C. T., Kim, E.-H., Luong, T. T., Pyo, S., Rhee, D.-K. Tags: BACTERIA Source Type: research