Combinatorial effect of curcumin and tumor necrosis factor- & #945;-related apoptosis-inducing ligand (TRAIL) in induction of apoptosis via inhibition of nuclear factor kappa activity and enhancement of caspase-3 activity in chronic myeloid cells: An In-vitro study
Conclusion: Our results conclude that curcumin and TRAIL effectively induce the apoptosis through the inhibition of NFkB activity and by enhancing the caspase-3 activity. Thus, curcumin may prove as a potent inhibitor of NFkB by representing its role in cancer pathogenesis, especially in chronic myeloid leukemia cells.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Bushra Iqbal Archna Ghildiyal Shraddha Singh Sahabjada Siddiqui Pratibha Kumari M Arshad AA Mahdi Source Type: research
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