The Associations Between CYP2D6 Metabolizer Status and Pharmacokinetics and Clinical Outcomes of Venlafaxine: A Systematic Review and Meta-Analysis

Conclusions CYP2D6 metabolizer status had significant influence on venlafaxine pharmacokinetics, but insufficient evidence demonstrated that CYP2D6 metabolizer status was associated with its therapeutic effects and overall rate of adverse events, which provided further evidence regarding the relationship between CYP2D6 metabolizer status and venlafaxine. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Pharmacopsychiatry - November 28, 2018 Category: Psychiatry Authors: Lin, Xiao-Qian Wang, Ping Cai, Wen-Ke Xu, Gui-Li Yang, Mei Zhou, Meng-Di Sun, Mei He, Fang He, Gong-Hao Tags: Original Paper Source Type: research