Kidney fibrosis induced by various irrigation pressures in mouse models of mild and severe hydronephrosis

ConclusionCompared with mild hydronephrosis, renal fibrosis in severe hydronephrosis is more severe and its tolerance to perfusion pressure is lower. These changes may be related to the TGF- β signalling pathway.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research