A birch sublingual allergy immunotherapy tablet reduces rhinoconjunctivitis symptoms when exposed to birch and oak and induces IgG4 to allergens from all trees in the birch homologous group

ConclusionThis trial demonstrates that the SQ tree SLIT ‐tablet reduce ARC symptoms triggered by birch or oak pollen. The optimal dose for further development was 12 DU. Clinical and immunological findings suggest that the tablet may be used to treat allergies to all species within the birch homologous group.

https://onlinelibrary.wiley.com/doi/abs/10.1111/all.13606?af=R

Source: Allergy - November 22, 2018 Category: Allergy & Immunology Authors: Peter Couroux, Henrik Ipsen, Brian Sonne Stage, Jakob Thomas Damkj ær, Maria Abildgaard Steffensen, Anne Marie Salapatek, Kaare Lund, Peter Adler Würtzen Tags: ORIGINAL ARTICLE Source Type: research