Key amino acid residues of the AGT1 permease required for maltotriose consumption and fermentation by Saccharomyces cerevisiae

ConclusionsBased on the results obtained with mutant proteins, molecular docking and the localization of amino acid residues, we propose a transport mechanism for theAGT1 permease.Significance and Impact of the StudyOur results present new insights into the structural basis for activeα–glucoside‐H+ symport activity by yeast transporters, providing the molecular bases for improving the catalytic properties of this type of sugar transporters.This article is protected by copyright. All rights reserved.

Source: Journal of Applied Microbiology - November 22, 2018 Category: Microbiology Authors: D ébora Trichez, Marilia M. Knychala, Catarina M. Figueiredo, Sérgio L. Alves, Marcia A. da Silva, Luiz C. Miletti, Pedro S. de Araujo, Boris U. Stambuk Tags: Original Article Source Type: research