Somatic genetic alterations in synchronous and metachronous low ‐grade serous tumours and high‐grade carcinomas of the adnexa

ConclusionsOur results suggest that progression from SBT to HGSC may take place in a subset of cases, and that at least some of the rare HGSCs lackingTP53 mutations may be derived from a low ‐grade serous precursor.This article is protected by copyright. All rights reserved.

Source: Histopathology - November 22, 2018 Category: Pathology Authors: Rajmohan Murali, Pier Selenica, David N. Brown, R. Keira Cheetham, Raghu Chandramohan, Nidia L. Claros, Nancy Bouvier, Donavan T. Cheng, Robert A. Soslow, Britta Weigelt, W. Glenn McCluggage Tags: Original Article Source Type: research