Silencing Long Non-Coding RNA ST3GAL6-AS1 Inhibits Adhesion and Migration of Myeloma Cells in Vitro

Conclusions: Knockdown of ST3GAL6-AS1 in MM cells significantly inhibits adhesion, migration and invasion in vitro, indicating that ST3GAL6-AS1 may play an important role in the malignant behavior of MM cells. The co-expression between ST3GAL6-AS1 and gene ST3GAL6 has been demonstrated in our previous study, which was further confirmed in present study. Researches are ongoing to address the potential mechanism among them in MM.Figure 1.DisclosuresNo relevant conflicts of interest to declare.

Source: Blood - November 21, 2018 Category: Hematology Authors: Shen, Y., Feng, Y., Chen, H., Jia, Y., Peng, Y., Zhang, R., Yang, Y., Wang, J.-L., Bai, J., Wang, F.-X., Xu, Y., Hu, J., He, A. Tags: 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster III Source Type: research