Does nasal rinsing reduce the need for repeat nasal brushing biopsies in a primary ciliary dyskinesia (PCD) diagnostic service? A pilot study.

Conclusion: This small pilot study suggests NR reduces mucus impedance in nasal brushing biopsies but this does not affect the need to repeat HSVM in equivocal cases. Secondary ciliary dyskinesia and PCD with subtle cilia abnormalities is likely to be the main reason for equivocal HSVM. Further research is needed.

Source: European Respiratory Journal - November 19, 2018 Category: Respiratory Medicine Authors: Harris, A., Keenan, V., Friend, A., Wilkins, H., Rubbo, B., Jackson, C., Coles, J., Thompson, J., Packham, S., Macleod, E., Nyimbili, E., Walker, W., Lucas, J., Evans, H. Tags: Paediatric respiratory epidemiology Source Type: research