Cytokine profiles in cerebrospinal fluid of patients with meningitis at a tertiary general hospital in China.

CONCLUSIONS: The excessive activation of immune response characterized by elevated levels of CSF Th1-, Th2- and Th17-type cytokines has been observed during CNS infection. Furthermore, we observed negative correlations between CSF IL-6 levels and CSF glucose and CSF/blood glucose ratio in CNS infection. And we suggested that combined CSF IL-6 levels with CSF glucose may serve as a novel biomarker pool for the differential of CNS infection.
PMID: 30448438 [PubMed - as supplied by publisher]

Source: Journal of Microbiology, Immunology, and Infection - November 9, 2018 Category: Microbiology Authors: Liu Q, Gao Y, Zhang B, Sun F, Yang Q, Liu Y, Wu J, Chen K, Weng X, Zhang W, Huang R, Shao L Tags: J Microbiol Immunol Infect Source Type: research