Pharmacokinetics and pharmacodynamics of bcx7353, an oral plasma kallikrein inhibitor, in healthy japanese subjects

BCX7353 is an oral kallikrein inhibitor being studied for prevention and treatment of hereditary angioedema (HAE) attacks in Western patients. HAE afflicts all ethnic groups. An ethnobridging study was conducted in healthy Japanese subjects to support development of BCX7353 in Japanese HAE patients.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: P158 Source Type: research