Novel understandings of host cell mechanisms involved in chronic lung infection: Pseudomonas aeruginosa in the cystic fibrotic lung

As one of the most debilitating and underdiagnosed hereditary conditions across the globe, cystic fibrosis requires intensive support from the healthcare system – particularly due to the increased susceptibility to chronic infection and resulting respiratory failure which can rapidly lead to death. In turn, the prevalence and action of a certain strain of bacterium – Pseudomonas aeruginosa – has gained a great deal of interest. Life-threatening chroni c infections by P. aeruginosa have been shown to involve biofilm formation, proliferation and the release of quorum-sensing signaling molecules.

Source: Journal of Infection and Public Health - November 17, 2018 Category: International Medicine & Public Health Authors: Peter Anto Johnson Source Type: research