Acrodermatitis chronica atrophicans: various faces of the late form of Lyme borreliosis.
Conclusions: Despite raising awareness of Lyme borreliosis, late forms of the disease such as ACA are still observed. Acrodermatitis chronica atrophicans skin lesions may be located in non-characteristic areas, e.g. abdominal skin. Symptoms are not irritating or painful, therefore patients do not seek medical help. The effect of antibiotic treatment varies. PMID: 30429707 [PubMed]
The objective of this study was to describe the perioperative morbidity of patients with class III morbid obesity undergoing hysterectomy form benign disease.
A painless progressive verrucous skin plaque in an endemic area should raise suspicion for blastomycosis resulting in prompt biopsy with fungal stains and culture. Skin is a common extrapulmonary site. Itraconazole is treatment of choice. AbstractA painless progressive verrucous skin plaque in an endemic area should raise suspicion for blastomycosis resulting in prompt biopsy with fungal stains and culture. Skin is a common extrapulmonary site. Itraconazole is treatment of choice.
AbstractThe aim of this research was to differentiate dapagliflozin, empagliflozin, and canagliflozin based on their capacity to inhibit sodium ‐glucose cotransporter (SGLT) 1 and 2 in patients with type 2 diabetes, using a previously developed quantitative systems pharmacology model of renal glucose filtration, reabsorption, and excretion. The analysis was based on pooled, mean study‐level data on 24‐hour urinary glucose excretion (U GE), average daily plasma glucose and estimated glomerular filtration rate collected from phase 2 clinical trials of SGLT2 inhibitors. Variations in filtered glucose across clinical stu...
Publication date: Available online 26 February 2020Source: Journal of EthnopharmacologyAuthor(s): Shanika Karunasagara, Geum-Lan Hong, Se-Ra Park, Na-Hyun Lee, Da-Young Jung, Tae Won Kim, Ju-Young Jung
ConclusionsThis is the first study demonstrating that twice/day insulin glargine reduced the rate of predose hyperglycemia without increasing the risk of hypoglycemia in critically ill patients. A large randomized study is needed to confirm the safety and efficacy of twice/day glargine in the critically ill.
ConclusionPatients with diabetes mellitus show a higher level of tooth loss than those without diabetes mellitus, based on the results of a population ‐based survey.
ConclusionsFindings suggest small fibre structural and functional deficits in chronic WAD, implicating potential involvement of small fibre pathology.
Authors: Honda H, Hanayama Y, Obika M, Hasegawa K, Hamahara J, Kishida M, Hagiya H, Ogawa H, Kataoka H, Otsuka F Abstract A relationship between diabetes and depression is apparent. To clarify the clinical relevance of diabetic patients' gastroesophageal symptoms to their psychological status, we retrospectively analyzed the data from a Selfrating Depression Scale (SDS) and a Frequency Scale for Symptoms of Gastroesophageal reflux disease (FSSG) among 143 type 2 diabetic patients who visited a general medicine department. Among the 45 Japanese patients enrolled, the group with relatively high SDS scores (≥ 36) s...