Clinical outcomes in hemophilia A patients undergoing tailoring of prophylaxis based on population-based pharmacokinetic dosing
Standard prophylaxis dosing based on bodyweight may result in over- or under-dosing due to interpatient variability. Adopting individual pharmacokinetic (PK) based tailoring may improve adherence to treatment guideline, and consequently clinical outcomes. Here we report clinical observations performed across the adoption of individual PK based tailoring in a single center in Japan.
Source: Thrombosis Research - Category: Hematology Authors: Azusa Nagao, Cindy H.T. Yeung, Federico Germini, Takashi Suzuki Tags: Full Length Article Source Type: research