Novel rearrangements involving the RET gene in papillary thyroid carcinoma

ConclusionsRUFY2-RET and KIAA1468-RET are novel RET/PTC rearrangements. The fusions were previously described in non–small cell lung cancer. The rearrangement results in a fusion of the RET tyrosine kinase to regulatory domains of RUFY2 and KIAA1468.
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research