Processing and Presentation of Non-Conventional MHC Ligands (R01 Clinical Trial Not Allowed)

Funding Opportunity PA-19-067 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites applications to characterize antigen processing and presentation mechanisms used in the generation of novel peptidic and non-peptidic ligands presented by classical and non-classical MHC class I and class II molecules, and to determine the contribution of these unique antigenic ligands to: protective immune responses to infectious pathogens and/or vaccines; pathogen-associated immune pathogenesis; and/or in the induction/progression or prevention of immune-mediated diseases. These studies may facilitate the development of novel tools and reagents to advance design of immune-based therapeutics and vaccines.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding