Reward-driven decision-making impairments in schizophrenia

The ability to use feedback to guide optimal decision-making is essential for goal-directed behaviour. While impairments in feedback-driven decision-making have been associated with schizophrenia and depression, this has been examined primarily in the context of binary probabilistic choice paradigms. In real-world decision-making, however, individuals must make choices when there are more than two competing options that vary in the frequency and magnitude of potential rewards and losses. Thus, the current study examined win-stay/lose-shift (WSLS) behaviour on the Iowa Gambling Task (IGT) in order to evaluate the influence of immediate rewards and losses in guiding real-world decision-making in patients with schizophrenia and major depressive disorder.

Source: Schizophrenia Research - November 12, 2018 Category: Psychiatry Authors: Sarah Saperia, Susana Da Silva, Ishraq Siddiqui, Ofer Agid, Z. Jeff Daskalakis, Arun Ravindran, Aristotle N. Voineskos, Konstantine K. Zakzanis, Gary Remington, George Foussias Source Type: research