Intestinal immune dysregulation driven by dysbiosis promotes barrier disruption and bacterial translocation in rats with cirrhosis

Conclusion: The intestinal mucosa of rats with cirrhosis acquires a proinflammatory profile of immune dysregulation that parallels the severity of cirrhosis. This impaired intestinal immune response is driven by gut dysbiosis and leads to disrupted barrier function, promoting GBT.This article is protected by copyright. All rights reserved.

Source: Hepatology - November 10, 2018 Category: Internal Medicine Authors: Leticia Mu ñoz, María‐José Borrero, María Úbeda, Elisa Conde, Rosa del Campo, Macarena Rodríguez‐Serrano, Margaret Lario, Ana‐María Sánchez‐Díaz, Oscar Pastor, David Díaz, Laura García‐Bermejo, Jorge Monserrat, Melchor Ál Tags: Original Source Type: research