Effect of sperm storage and selection techniques on sperm parameters.

This article will discuss these sperm preservation and selection techniques. PMID: 25354153 [PubMed - as supplied by publisher]
Source: Systems Biology in Reproductive Medicine - Category: Reproduction Medicine Authors: Tags: Syst Biol Reprod Med Source Type: research

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Authors: Cao M, Zhou M, Zhang J Abstract Patients with metastatic colorectal cancer (mCRC) beyond second line treatment have a poor prognosis. Regorafenib, TAS-102, fruquintinib, panitumumab and cetuximab are recommended single-agent chemotherapy regimens for patients exhibiting disease progression, this meta-analysis aimed to evaluate the efficacy and safety of these regimens in randomized controlled trials (RCTs). Eight RCTs with 3,832 cancer patients were included. Results showed that there was no significant difference in OS and PFS among the four drugs when comparing all patients or patients who have the KRAS ...
Source: Journal of Chemotherapy - Category: Cancer & Oncology Tags: J Chemother Source Type: research
CONCLUSION: The best of our knowledge it is the third description of brachial plexus schwannoma associated with breast cancer and the first with a synchronous association. The knowledge of this pathology and its potential to alter treatment justify the reporting of the present case. PMID: 32083563 [PubMed - as supplied by publisher]
Source: Breast Disease - Category: Cancer & Oncology Tags: Breast Dis Source Type: research
Conclusion: Cytokine-induced killer cell immunotherapy combined with first-line chemotherapy could significantly improve the OS and PFS of patients with mCRC, particularly for patients with metastatic colon cancer. PMID: 32076550 [PubMed]
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Tags: Clin Transl Immunology Source Type: research
Publication date: Available online 21 February 2020Source: Chinese Chemical LettersAuthor(s): Lei Zhou, Chang Du, Rong Zhang, Changming DongAbstractWe developed one-pot aqueous copolymerization of two dopamine prodrugs to prepare dual drugs-conjugated polydopamine nanoparticles (PDOXCBs), which integrated near infrared (NIR)-mediated photothermal effect with cocktail chemotherapy into one copolymer nanoparticle. Upon a mild NIR irradiation (808 nm, 1 W/cm2, 10 min), PDOXCBs gradually heated aqueous solution over 12.8―13.9 °C, which accordingly enhanced in vitro dual doxorubicin (DOX) and c...
Source: Chinese Chemical Letters - Category: Chemistry Source Type: research
Conclusion: The results of our unsupervised classification algorithm based on three variables of laboratory tests correlated well with the neurologists' diagnoses. PMID: 32076460 [PubMed - in process]
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Publication date: March 2020Source: European Journal of Surgical Oncology, Volume 46, Issue 3Author(s): Laura Lorenzon, Serge Evrard, Geerard Beets, Santiago Gonzalez-Moreno, Tibor Kovacs, Domenico D'Ugo, Karol Polom, CORSiCA Study - EYSAC.1 Study GroupAbstractBackgroundColorectal cancer mortality presents world-wide variation. In rectal cancers presenting a complete/nearly-complete tumor response (ypT0/ypTis) following neoadjuvant treatment, the features correlated to nodal metastases and relapses still need to be defined.MethodsAn international cohort study enrolling ypT0/ypTis rectal cancers surgically treated from 2012...
Source: European Journal of Surgical Oncology (EJSO) - Category: Surgery Source Type: research
We describe below a patient who has shown a response to combination of chemotherapy with Elenagen, a plasmid encoding p62. Elenagen was tested in a previous phase I/II study in patients with refractory solid tumors and shown to be safe. Also, plasmid ability to halt tumor progression and restore sensitivity to chemotherapy was found. Preclinical data supports effects on tumor grade and change the tumor's microenvironment in spontaneous canine breast cancers. We describe here a 48-year old female with triple-negative and BRCA1/2-negative breast cancer who had a primary resistance to chemotherapy and negative dynamics despit...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
ConclusionNivolumab appeared to be safe and effective in Taiwanese patients. These interim results suggest that nivolumab is a suitable treatment option for this population.Clinical trial registrationNCT02582125.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
ConclusionsDelineation of post NACT excision cavity as POC for boost radiotherapy is safe. Clips serve as a good surrogate for CTV delineation in 75% patients.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
Publication date: Available online 21 February 2020Source: Reports of Practical Oncology &RadiotherapyAuthor(s): Christian H. Flores-Balcázar, Ma. L. Flores-Luna, Cynthia M. Villarreal-Garza, Juan E. Bargalló-RochaAbstractAimThe goal of this study was to determine whether a delay in starting treatment via surgery or neoadjuvant chemotherapy is related to a decrease in cancer-specific survival (CSS) in women with operable breast cancer (BrCr).BackgroundLimited medical infrastructure and a lack of cancer prevention awareness in low- and middle-income countries have caused high BrCr incidence and mortality r...
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
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