Adipsin, MIP-1b, and IL-8 as CSF Biomarker Panels for ALS Diagnosis.

In this report, we analyzed 19 different cytokines and growth factors in the cerebrospinal fluid of 77 ALS patients and 13 controls by decision tree and PanelomiX program. Results showed an increase of Adipsin, MIP-1b, and IL-6, associated with a decrease of IL-8 thresholds, related with ALS patients. This biomarker panel analysis could represent an important aid for diagnosis of ALS alongside the clinical and neurophysiological criteria. PMID: 30405855 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30405855?dopt=Abstract

Source: Disease Markers - November 9, 2018 Category: Laboratory Medicine Tags: Dis Markers Source Type: research

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