Neuroprotective and antihyperalgesic effects of orexin-A in rats with painful diabetic neuropathy

Diabetes mellitus is related to the development of neuronal tissue injury in different peripheral and central nervous system regions. A common complication of diabetes is painful diabetic peripheral neuropathy (PDN). We have studied the neuroprotective and anti-nociceptive properties of neuropeptide orexin-A in an animal experimental model of diabetic neuropathy.

Source: Neuropeptides - November 8, 2018 Category: Neuroscience Authors: Seddigheh Niknia, Ayat Kaeidi, Mohammad Reza Hajizadeh, Mohammad Reza Mirzaei, Alireza Khoshdel, Zahra Hajializadeh, Mohammad Ali Fahmidehkar, Mahdi Mahmoodi Source Type: research