InDevR's VaxArray platform to tackle measles-Rubella vaccines

(InDevR, Inc.) InDevR announced today that it will pursue proof of concept development for new VaxArray potency assays for measles (M) and rubella vaccines sponsored by the Bill&Melinda Gates Foundation. The long-term objective is to create in vitro measles and rubella potency assays in order to deliver high quality MR vaccines to market faster and with lower production costs. The project will leverage the multiplexed VaxArray platform, which was first developed and validated for more efficient potency testing of influenza vaccines.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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It's too soon to know for sure how the tale of the novel coronavirus will play out,but at this point we have a pretty good idea. A stipulation in both of the scenarios at the linked essay is that yeah, it gets loose into the wild and eventually can show up anywhere in the world. I think that's pretty much definitely going to happen if it hasn't already.Scenario number 1, and most likely, in my view, it will just be one more virus that causes what amounts to a common cold and in a few people who are otherwise debilitated goes on to be complicated by pneumonia. In that case, for a year or two it will circulate as a novel vir...
Source: Stayin' Alive - Category: American Health Source Type: blogs
Authors: Albertsen N, Lynge AR, Skovgaard N, Olesen JS, Pedersen ML Abstract In order to estimate the current coverage rate among all children in Greenland, we conducted an observational cross-sectional study identifying all children in Greenland eligible for a vaccination between 1 March 2018 and 16 June 2019. we found an overall national coverage of 85.4%. The national coverage for the vaccinations given at birth was 97.1%, dropping to 94.3%, 87.7% and 83.6% at ages 3, 5 and 12 months. Among children eligible for the Measles, Mumps and Rubella-vaccinations, the national coverage was 76.9% for children aged 15 mon...
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research
You’ve done it! You’ve taken that last birth control pill, removed your IUD, or stopped using your contraceptive method of choice. You’ve made the decision to try to conceive a pregnancy, and while this is an exciting time in your life, it can also feel overwhelming. There is so much advice around fertility and pregnancy, and sifting through it all just isn’t possible. For many mothers, their goals crystallize around ensuring that their baby is healthy. Evidence-based steps that may prevent birth defects January is Birth Defects Prevention Month, so we want to focus on things you can do to reduce th...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Family Planning and Pregnancy Fertility Vaccines Women's Health Source Type: blogs
The rise of vaccine-preventable illnesses, such as measles and hepatitis, in the United States and around the globe has been alarming in recent years. For women — especially those hoping to become pregnant, as well as women who are pregnant or have recently had a baby — vaccines can be a worrisome topic. There are many misconceptions about vaccine safety in and around pregnancy that can lead to confusion and unnecessary fear of a lifesaving medical tool. As a practicing ob/gyn, I often discuss vaccines with my patients and help them sort out fears versus facts. Which vaccines should you consider before concepti...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Parenting Pregnancy Vaccines Women's Health Source Type: blogs
AbstractThe role of vaccination in the development of Guillain-Barr é syndrome (GBS) is controversial, although cases of GBS have been reported following a wide range of vaccines. A nested case–control study was conducted between January 2011 and December 2015 in three Chinese cities. Four controls were matched to a case by gender, age, address and index date. An independent expert committee validated the diagnoses of cases and controls according to the Brighton Collaboration GBS case definition. Data on vaccinations were obtained from computerized vaccination records. Causal relations were assessed by conditi...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
Purpose of review Studying primary immunodeficiencies (PIDs) provides insights into human antiviral immunity in the natural infectious environment. This review describes new PIDs with genetic defects that impair innate antiviral responses. Recent findings New genetic defects in the interferon (IFN) signaling pathway include IFNAR1 deficiency, which causes uncontrolled infections with measles-mumps-rubella or yellow fever vaccines, and possibly also cytomegalovirus (CMV); and IRF9 deficiency, which results in influenza virus susceptibility. Genetic defects in several pattern recognition receptors include MDA5 deficienc...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research
Abstract The Advisory Committee on Immunization Practices (ACIP) recommends that children be vaccinated against 14 potentially serious illnesses during the first 24 months of life (1). CDC used data from the National Immunization Survey-Child (NIS-Child) to assess vaccination coverage with the recommended number of doses of each vaccine at the national, state, territorial, and selected local levels* among children born in 2015 and 2016. Coverage by age 24 months was at least 90% nationally for ≥3 doses of poliovirus vaccine, ≥1 dose of measles, mumps, and rubella vaccine (MMR), ≥3 doses of hepatitis B vac...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
In conclusion, European countries now have more comprehensive national vaccination programs for HCP, however there are still gaps. Given the recent large outbreaks of vaccine-preventable diseases in Europe and the occupational risk for HCP, vaccination policies need to be expanded and strengthened in several European countries. Overall, vaccination policies for HCP in Europe should be periodically re-evaluated in order to provide optimal protection against vaccine-preventable diseases and infection control within healthcare facilities for HCP and patients. PMID: 31623916 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Carter Roberts’ motorized wheelchair didn’t arrive until the day he died. It had been a long time coming and his parents had fought hard to get it. The chair cost more than $32,000 and the insurance companies wouldn’t cover it, so the family went to court. One insurer eventually agreed to pay for some components of the chair but not the whole thing. And then none of it mattered anyway. On Sept. 22, 2018, the Roberts’ doorbell rang and the chair was delivered. Also on Sept. 22, 2018, Carter died, just three months shy of his sixth birthday. He had been largely paralyzed for the final two years of his...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease viruses Source Type: news
ABSTRACT Measles is an acute febrile exanthematic disease of viral etiology, highly contagious, being the cause of morbidity and mortality of children in developing countries, whereas it has become rarer in developed countries due to vaccination. Its differential diagnosis should be made with other childhood viral respiratory diseases such as influenza, rhinovirus and adenovirus, and exanthematic febrile diseases such as rubella, roseola and varicella. In tropical regions, it should be performed with dengue, zika and chikungunya. Its clinical picture presents the following phases: incubation, usually asymptomatic; a prodro...
Source: Jornal Brasileiro de Patologia e Medicina Laboratorial - Category: Pathology Source Type: research
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