Differential involvement of TAK1, RIPK1 and NF- κB signaling in Smac mimetic-induced cell death in breast cancer cells.

In conclusion, TAK1, receptor-interacting kinase 1 (RIPK1) as well as canonical and non-canonical NF-κB signaling are differentially involved in SM-induced cell death in breast cancer cells. These findings contribute to a better understanding of SM-induced signaling pathways. PMID: 30391931 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30391931?dopt=Abstract

Source: Biological Chemistry - November 6, 2018 Category: Chemistry Tags: Biol Chem Source Type: research