Mutation and Clinical Characteristics of Autosomal-Dominant Hereditary Spastic Paraplegias in China.

Conclusions: Our data confirm that hereditary spastic paraplegias in China represent a heterogeneous group of genetic neurodegenerative disorders in autosomal-dominant and apparently sporadic forms. Novel genotype-phenotype correlations were established. © 2014 S. Karger AG, Basel.
PMID: 25341883 [PubMed - as supplied by publisher]

Source: Neuro-Degenerative Diseases - October 22, 2014 Category: Neurology Authors: Luo Y, Chen C, Zhan Z, Wang Y, Du J, Hu Z, Liao X, Zhao G, Wang J, Yan X, Jiang H, Pan Q, Xia K, Tang B, Shen L Tags: Neurodegener Dis Source Type: research