Everolimus Exposure and Early Metabolic Response as Predictors of Treatment Outcomes in Breast Cancer Patients Treated with Everolimus and Exemestane

ConclusionsOur results show that everolimus toxicity is related to everolimus Ctrough. No relation was observed between everolimus exposure and treatment effectiveness. An early FDG-PET can identify patients at high risk of nonresponse. These results warrant further validation.Clinicaltrials.gov identifier: NCT01948960.
Source: Targeted Oncology - Category: Cancer & Oncology Source Type: research