Reactive sulfur species (RSS): persulfides, polysulfides, potential, and problems.

Reactive sulfur species (RSS): persulfides, polysulfides, potential, and problems. Curr Opin Chem Biol. 2018 Sep 19;49:1-8 Authors: Lau N, Pluth MD Abstract Sulfur is a crucial element in biology due to its unique properties and wide range of accessible oxidation states. This reactivity gives rise to the generation of reactive sulfur species (RSS), which have emerged as a diverse class of small molecules and functional groups with important roles in chemical biology and bioinorganic chemistry. In this review, we focus on basic properties of simple RSS, highlight recent insights into the interconnectivity of RSS with reactive nitrogen species, and discuss recent advances in methods for RSS detection and measurement. Finally, we highlight key reactivity considerations that must be taken into account when working with RSS and interpreting the outcomes of labeling methods for RSS and related species. PMID: 30243097 [PubMed - as supplied by publisher]
Source: Current Opinion in Chemical Biology - Category: Biochemistry Authors: Tags: Curr Opin Chem Biol Source Type: research