Congenital HIV: Prevention of Maternal to Child Transmission.

Congenital HIV: Prevention of Maternal to Child Transmission.
Adv Neonatal Care. 2018 Oct;18(5):330-340
Authors: Lynch NG, Johnson AK
Abstract
BACKGROUND: Human immunodeficiency virus (HIV) is caused by a cytopathic lentivirus. HIV without adequate treatment during pregnancy can result in maternal to child transmission (MCT) of the virus. Sequelae can include severe lifelong morbidities, shorter life expectancies, and high mortality rates without antiretroviral therapy.
PURPOSE: To discuss epidemiological trends, pathophysiology, and clinical care guidelines including those for diagnosis, treatment, and management of MCT of HIV in the United States. To emphasize the importance of prompt identification, prophylaxis, and treatment of at-risk infants.
METHODS: PubMed, CINAHL, MEDLINE, and Google Scholar were used to search key words-maternal to child transmission, HIV, HIV in pregnancy, and neonatal HIV-for articles that were relevant and current. The World Health Organization, Centers for Disease Control and Prevention, and UNICEF were also utilized for up-to-date information on the topic.
FINDINGS: Timely identification, intervention, and treatment are necessary to prevent MCT of HIV. Membrane rupture duration is not associated with higher transmission rates with adequate viral suppression.
IMPLICATIONS FOR PRACTICE: An evidence-based maternal/neonatal collaborative approach to care for the prevention a...

Source: Advances in Neonatal Care - September 22, 2018 Category: Nursing Authors: Lynch NG, Johnson AK Tags: Adv Neonatal Care Source Type: research