Obesityglucose Tolerance And Insulin Sensitivity Define Adipocyte Transcriptional Programs In Human Obesity

ConclusionSOur study showed that glucose intolerance and insulin resistance co-operate to remodel adipocyte transcriptome. We also identified the Nuclear Export Mediator Factor (NEMF) and the Ectoderm-Neural Cortex 1 (ENC1) as novel potential targets in the management of metabolic health in human obesity.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research