Bioequivalence and Pharmacokinetics of Bisoprolol –Amlodipine 5 mg/5 mg Combination Tablet versus Bisoprolol 5 mg Tablet and Amlodipine 5 mg Tablet: An Open-Label, Randomized, Two-Sequence Crossover Study in Healthy Chinese Subjects

ConclusionsBioequivalence was achieved for bisoprolol and amlodipine FDC under both fasting and fed conditions, and all treatments were safe and well tolerated by all study subjects.Trial RegistrationClinicalTrials.gov: NCT03226275.

http://link.springer.com/10.1007/s40261-018-0700-y

Source: Clinical Drug Investigation - September 19, 2018 Category: Drugs & Pharmacology Source Type: research