Head impulse gain and saccade analysis in pontine-cerebellar stroke and vestibular neuritis

Conclusion: HIT gains and compensatory saccades differ between PCS and VN. VN was characterized by unilateral gain deficits with asymmetric large saccades, AICA stroke by more symmetric bilateral gain reduction with smaller saccades, and PICA stroke by contralesional gain bias with the smallest saccades. Saccade and gain asymmetry should be investigated further in future diagnostic accuracy studies. Classification of evidence: This study provides Class II evidence that aVOR testing accurately distinguishes patients with PCS from VN (sensitivity 94%–97%, specificity 90%–100%).

http://www.neurology.org/cgi/content/short/83/17/1513?rss=1

Source: Neurology - October 20, 2014 Category: Neurology Authors: Chen, L., Todd, M., Halmagyi, G. M., Aw, S. Tags: ARTICLE Source Type: research