Characteristic molecular and proteomic signatures of drug‐induced liver injury in a rat model

In conclusion, the data of different DILI‐causing drug treatments from genomic analysis in a rat model suggest that DILI‐specific molecular signatures can discriminate different patterns of DILI at an early exposure time point, and that they provide useful information for mechanistic studies that may lead to a better understanding of the molecular basis of DILI. Copyright © 2014 John Wiley & Sons, Ltd.

Source: Journal of Applied Toxicology - September 18, 2014 Category: Toxicology Authors: Jung Woo Eun, Hyun Jin Bae, Qingyu Shen, Se Jin Park, Hyung Seok Kim, Woo Chan Shin, Hee Doo Yang, Chan Young Jin, Jueng Soo You, Hyun Joo Kang, Hoguen Kim, Young Min Ahn, Won Sang Park, Jung Young Lee, Suk Woo Nam Tags: Research Article Source Type: research