An optimal protocol for measurement of corticospinal excitability, short intracortical inhibition and intracortical facilitation in the rectus femoris

The study aimed to determine the optimal application of single- and paired-pulse transcranial magnetic stimulation (TMS) in the rectus femoris. Twenty-nine male adults participated in the study, which involved 5 separate experiments. Experiments 1 to 3 assessed the effect of conditioning stimulus (CS) intensity (60, 70, 80 and 90% active motor threshold, AMT), contraction strength (5, 10, 20 and 50% maximum voluntary contraction, MVC), and inter-stimulus interval (ISI, 2 –5 ms for short-interval intracortical inhibition, SICI and 10–15 ms for intracortical facilitation, ICF) on SICI and ICF.

Source: Journal of the Neurological Sciences - September 5, 2018 Category: Neurology Authors: Callum G. Brownstein, Paul Ansdell, Jakob Škarabot, Glyn Howatson, Stuart Goodall, Kevin Thomas Source Type: research