Interconnected clusters of invasive meningococcal disease due to Neisseria meningitidis serogroup C ST-11 (cc11), involving bisexuals and men who have sex with men, with discos and gay-venues hotspots of transmission, Tuscany, Italy, 2015 to 2016.
Interconnected clusters of invasive meningococcal disease due to Neisseria meningitidis serogroup C ST-11 (cc11), involving bisexuals and men who have sex with men, with discos and gay-venues hotspots of transmission, Tuscany, Italy, 2015 to 2016. Euro Surveill. 2018 Aug;23(34): Authors: Miglietta A, Fazio C, Neri A, Pezzotti P, Innocenti F, Azzari C, Rossolini GM, Moriondo M, Nieddu F, Iannazzo S, D'Ancona F, Maraglino FP, Guerra R, Rezza G, Voller F, Stefanelli P Abstract In 2015 an increased incidence of invasive meningococcal disease due to serogroup-C (MenC) occurred in Tuscany, Italy. This led the Regional Health Authority of Tuscany to implement a reactive immunisation campaign and to launch an epidemiological field investigation aiming to address targeted immunisation interventions. In 2011-14, 10 MenC cases had been reported compared with 62 cases in 2015-16. The case fatality rate was 21% (n = 13) and 51 cases (82.3%) were confirmed as C:P1.5-1,10-8:F3-6:ST-11(cc11). Overall, 17 clusters were recognised. Six discos and four gay-venues were found to have a role as transmission-hotspots, having been attended by 20 and 14 cases in the 10 days before symptoms onset. Ten and three cases occurred, respectively, among men who have sex with men (MSM) and bisexual individuals, who were involved in 11 clusters. In addition, heterosexual cases (n = 5) attending gay-venues were also found. Secondary cases were not identified. Mo...
Objectives: To perform a comprehensive description of the epidemiology of Streptococcus pyogenes invasive disease in the pediatric population in 2 regions of Spain (Catalonia and Gipuzkoa) through 12 years. Methods: All S. pyogenes isolates causing invasive disease in pediatric patients between 2005 and 2016 were included. The emm-type and the presence of 13 exotoxin genes (speA, speB, speC, speF, speG, speH, speI, speJ, speK, speL, speM, smeZ, ssa and slo) were determined in all 93 available isolates and the Multi Locus Sequece Typing in 10% of isolates of each different emm-type. Results: Overall, 103 cases of S....
[WHO] Children in 19 Northern states to be vaccinated in largescale campaign implemented by the Government of Nigeria and WHO with Gavi support
A total of 30 per cent of parents surveyed said their children had missed one or more routine jabs including MMR, flu or meningitis. One in four claimed this is for 'safety concerns' about vaccines.
Authors: İşeri Nepesov M, Dinleyici M, Kılıç Ö, Ceyhan M, Gürler N, Dinleyici EÇ Abstract Streptococcus pneumoniae is a major cause of bacterial meningitis in children. It can progress and carries a serious risk of mortality and morbidity despite effective treatment. Cochlear implantation is a fairly successful procedure for restoring hearing in cases of sensorineural hearing loss. Moreover, patients with cochlear implants are at increased risk of contracting pneumococcal meningitis compared to the general population. The development of meningitis is associated with pathogens in the midd...
[This Day] Over 2 million children in Benue State are to be vaccinated during the 2019 integrated measles and meningitis campaign to hold from 16th to 23rd November, 2019 in the 277 wards across the 23 local government areas of Benue State. Executive Secretary, State Primary Health Care Board, Dr. Bem Ageda disclosed this during a media orientation meeting in Makurdi yesterday saying that both measles and meningitis immunisations so were to run concurrently. Ageda said a total of 1,108,990 children between the ages o
Neisseria meningitidis is a major global cause of meningitis and septicaemia worldwide and is associated with significant morbidity and mortality. Twelve meningococcal capsular groups have been identified, of which six (A, B, C, W, X and Y) are responsible for nearly all cases of invasive meningococcal disease (IMD), globally. Different capsular groups predominate in different geographical regions and can fluctuate over time, as new strains are introduced into susceptible populations or following new vaccination programmes.
CONCLUSIONS: The safety profile of RTS,S/AS01 in HIV-infected children was comparable to that of the comparator (meningococcal or rabies) vaccines. RTS,S/AS01 was immunogenic in HIV-infected children but antibody concentrations were lower than in children with an unknown or negative HIV status. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov: NCT00866619. PMID: 31708182 [PubMed - as supplied by publisher]
CONCLUSION: Timely notification of cases to health authorities was essential for the detection of the cluster and the rapid implementation of the vaccination campaign. No further cases occurred in the campus in the year following the vaccination campaign. This episode is the second cluster of MenW caused by the "UK-2013 strain" in a university since 2016. PMID: 31676065 [PubMed - as supplied by publisher]