Acupuncture as Adjuvant Therapy for the Management of Cervical Dystonia.

Conclusions: Acupuncture is feasible and safe as an adjunct treatment for chronic CD, and might be associated with subjective symptomatic benefits. PMID: 30147821 [PubMed]
Source: Acupuncture in Medicine - Category: Complementary Medicine Authors: Tags: Med Acupunct Source Type: research

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Credit: New York Times article, Jan. 19, 2016. The United States is in the midst of an opioid overdose epidemic. The rates of opioid addiction, babies born addicted to opioids, and overdoses have skyrocketed in the past decade. No population has been hit harder than rural communities. Many of these communities are in states with historically low levels of funding from the National Institutes of Health (NIH). NIGMS’ Institutional Development Award (IDeA) program builds research capacities in these states by supporting basic, clinical, and translational research, as well as faculty development and infrastructure impro...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - Category: Research Authors: Tags: Pharmacology Medicines Opioids Pain Source Type: blogs
ConclusionsAs DBS-MEG research continues to develop, we can expect to gain a better understanding of diverse pathophysiological networks and their response to DBS. This knowledge will improve treatment efficacy, reduce side-effects, reveal optimal surgical targets, and advance the development of closed-loop neuromodulation.
Source: Brain Stimulation - Category: Neurology Source Type: research
Thalamic Vim is a relay nucleus from the cerebellum and one of the targets for relieving symptoms of upper limb dystonia as well as tremor-dominant Parkinson ’s disease (PD) and essential tremor (ET). Beta oscillation is reported to be predominant from the single unit analysis in this nucleus in PD, ET and chronic pain (Basha D et al., 2014). We analyzed the Vim oscillation at rest in five cases with upper limb dystonia (four females, mean age of 31.2  yo) to elucidate whether beta oscillation is predominant also in dystonia.
Source: Clinical Neurophysiology - Category: Neuroscience Authors: Source Type: research
Ann Pierce-Jones used to be full of confidence but now lives "day-to-day" in chronic pain.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
Botulinum toxin serotype A (BoNT/A) was originally used in neurology for the treatment of dystonia and blepharospasms, but is now clinically used worldwide for the treatment of chronic migraine. Still, the possible mode of action of BoNT/A in migraine is not fully known. However, the mode of action of BoNT/A has been investigated in experimental pain as well as migraine models, which may elucidate the underlying mechanisms in migraine. The aim of this study was to review studies on the possible mode of action of BoNT/A in relation to chronic migraine treatment. Observations suggest that the mode of action of BoNT/A may not...
Source: Acta Neurologica Scandinavica - Category: Neurology Authors: Tags: REVIEW ARTICLE Source Type: research
Conclusions As DBS-MEG research continues to develop, we can expect to gain a better understanding of diverse pathophysiological networks and their response to DBS. This knowledge will improve treatment efficacy, reduce side-effects, reveal optimal surgical targets, and advance the development of closed-loop neuromodulation.
Source: Brain Stimulation - Category: Neurology Source Type: research
Nexeon Medsytems is a medical device company focused on providing innovative neurostimulation products for patients suffering from debilitating neurological diseases, including Parkinson’s and essential tremor. It was founded in 2005 with ...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Neurology Neurosurgery Source Type: blogs
Rationale: This case may be due to basal ganglia dysfunction, which was probably caused by abnormal activation of dopamine 1-like receptor (D1R) boosted by pramipexole binding on dopamine 3-like receptor (D3R) in a situation where D3R was overexpressed by the chronic treatment of L-dopa. Patient concerns: Striatal hand and foot deformities. Diagnoses: Striatal hand and foot deformities with CRPS. Interventions: Steroid treatemnt and withdrawal of the pramipexole. Outcomes: Recovered significantly. Lessons: Since the degree of overexpression of D3R is increased in a high dose of pramipexole, for patients with PD who ar...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Abstract Post-thoracotomy pain syndrome (PTPS) is a traumatic neuropathy that can affect as many as 50% of patients undergoing thoracotomy. Patients are often refractory to conservative management and may require multiple analgesics for adequate pain control. Botulinum toxin, derived from Clostridium botulinum, has many uses in treating conditions involving spasticity, dystonia, chronic migraine, and a variety of pain disorders including neuropathies. Botulinum toxin type A injections may provide an alternative or adjunct to improve symptom management in patients with PTPS. PMID: 28641445 [PubMed - as supplied by publisher]
Source: The American Journal of Hospice and Palliative Care - Category: Palliative Care Authors: Tags: Am J Hosp Palliat Care Source Type: research
ConclusionsGeriatric oral and maxillofacial dysfunctions could be better appreciated in the context of geriatric syndrome. The development of effective methods for evaluating the severity of these dysfunctions and the resulting frailty is essential.This article is protected by copyright. All rights reserved.
Source: Oral Diseases - Category: ENT & OMF Authors: Tags: Review Article Source Type: research
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