Synthesis and biological activity of a CXCR4-targeting bis(cyclam) lipid

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB01439F, PaperAnna Peters, Catriona McCallion, Andrew Booth, Julie Adams, Karen Rees-Unwin, Alain Pluen, John Burthem, Simon Webb A bis(cyclam)-capped cholesterol lipid designed to bind C-X-C chemokine receptor type 4 (CXCR4) was synthesised in good overall yield from 2-methoxyphenol through a seven step synthetic route, which also provided... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research