False positive screen test for mucopolysaccharidoses in healthy female newborns

ConclusionsThe altered electrophoretic pattern may be due to the presence of glycoproteins and not to specific GAGs, due to high levels of maternal hormones exposure during pregnancy. To our knowledge, this is the first time maternal estrogen hormones are proposed as a likely cause of false-positive urinary glycosaminoglycan screen test in healthy newborns.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research