Potential Role of Interleukin-25/Interleukin-33/Thymic Stromal Lymphopoietin-Fibrocyte Axis in the Pathogenesis of Allergic Airway Diseases.
Conclusions: In view of the redundancy of cytokines and "united airway" theory, we propose a new concept that IL-25/IL-33/TSLP-fibrocyte axis may play a vital role in the abnormal epithelial-mesenchymal crosstalk in some endotypes of AADs. This novel idea will guide potential new intervention schema for the common treatment of AADs sharing common pathogenesis in the future.
PMID: 30082531 [PubMed - in process]
Source: Chinese Medical Journal - Category: General Medicine Authors: Yao XJ, Liu XF, Wang XD Tags: Chin Med J (Engl) Source Type: research
More News: Allergy & Immunology | Asthma | China Health | Databases & Libraries | General Medicine | Hay Fever | Sinusitis | Study