Serum Leukotriene B4 Levels, Tonsillar Hypertrophy and Sleep-Disordered Breathing in Childhood

In children with snoring, increased production of leukotriene B4 (LTB4) may promote tonsillar hypertrophy and sleep-disordered breathing (SDB) or conversely SDB may enhance LTB4 synthesis. We explored whether: i) high LTB4 serum levels predict tonsillar hypertrophy; and ii) SDB severity correlates with LTB4 serum concentration.

Source: International Journal of Pediatric Otorhinolaryngology - August 7, 2018 Category: ENT & OMF Authors: Emmanouel Ι. Alexopoulos, George Haritos, Christina Befani, Georgia Malakasioti, Vassilis A. Lachanas, Panagiotis Liakos, Konstantinos Gourgoulianis, Athanasios G. Kaditis Source Type: research