Trans-catheter aortic valve implantation without contrast using the Lotus mechanically-expanded heart valve

We report a case of a TAVI in an 80-year-old patient with severe AS and significant chronic kidney disease (CKD), which was carried out without the use of contrast and with minimal procedural hypotension.Pre-procedural imaging was carried out using 3D trans-esophageal echocardiography (TEE) rather than computed tomography (CT) to avoid contrast administration. The Lotus valve (Boston Scientific, Marlborough, MA, USA) was chosen due to a number of design features which minimize both the need for contrast injection and procedural hypotension during valve positioning and deployment. The procedure was carried out successfully and produced an excellent result with no decline in renal function. We believe that the approach of using TEE and the mechanically-expanded Lotus valve illustrates an important therapeutic approach in patients with severe CKD.
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research

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Publication date: Available online 25 January 2019Source: Journal of Clinical and Experimental HepatologyAuthor(s): Lawrence AJ, Naveen Kalra, Anmol Bhatia, Radhika Srinivasan, Ajay Gulati, Rakesh Kapoor, Vikas Gupta, Radha K. Dhiman, Yogesh Chawla, Niranjan KhandelwalAimThe aim of this study was to compare the diagnostic adequacy of computed tomography (CT)–ultrasound (US) fusion image–guided fine needle aspiration (FNA) and US-guided FNA in patients with suspected hepatic metastases.MethodsThirty consecutive patients of either sex with known or unknown primary malignancy suspected of having liver metastases o...
Source: Journal of Clinical and Experimental Hepatology - Category: Gastroenterology Source Type: research
Publication date: Available online 21 February 2019Source: The Saudi Dental JournalAuthor(s): Muneera Abdulaziz AlHassan, Ahmed Fathi AlOmar, Rana Saud AlShagroudAbstractBackgroundSalivary glands swellings are frequently encountered in the dental clinic. Their causes include but not limited to neoplasm, infection, stone, and inflammation. Sublingual salivary gland enlargements are commonly caused by ranula, while neoplasms rarely occur and if found they tend to be malignant. Another cause is idiopathic hyperplasia of the sublingual gland (IHSG), which is characterized as asymptomatic swelling of unknown cause, protrude fro...
Source: The Saudi Dental Journal - Category: Dentistry Source Type: research
In conclusion,in vitro application of physiological levels of cyclic strain to tissue engineered heart valves seeded with autologous endothelial cells would be advantageous.
Source: Cardiovascular Engineering and Technology - Category: Cardiology Source Type: research
ConclusionThis brought to suggest that bone measurement by virtual method was highly accurate and reliable as in the conventional method. It is recommended for implementation in the future anthropological studies especially in countries with limited skeletal collection.
Source: Journal of Forensic and Legal Medicine - Category: Forensic Medicine Source Type: research
ConclusionsOur results provide evidence that PROMIS-57 and PROMIS-29 are highly reliable and valid instruments among kidney transplant recipients. We propose it as a valuable tool to assess important domains of the illness experience.
Source: Quality of Life Research - Category: Health Management Source Type: research
Conclusions: Our data indicate that higher TSH concentrations are positively correlated with CKD prevalence and that  a high TSH concentration is a risk factor for CKD development.Nephron
Source: Nephron - Category: Urology & Nephrology Source Type: research
Publication date: Available online 21 February 2019Source: American Journal of Kidney DiseasesAuthor(s): Vimal K. Derebail, Emily J. Ciccone, Qingning Zhou, R. Rosina Kilgore, Jianwen Cai, Kenneth I. AtagaRationale &ObjectiveProgression of chronic kidney disease (CKD) in sickle cell disease (SCD) and its risk factors remain poorly defined. We identified characteristics associated with CKD as well as decline in estimated glomerular filtration rate (eGFR) and presence of proteinuria over time in adults with SCD.Study DesignRetrospective observational study.Setting &ParticipantsPatients with SCD 18 years or older in a...
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
We report a case of a 30 years old woman who underwent surgical resection for a well-differentiated liposarcoma. CT scan revealed that the mass invaded the left perirenal fascia and displaced the descending colon, pancreas, and duodenum. Complete resection of tumour masses were performed and we opted against nephrectomy due to the tumor's histologic type, the patient's young age, and increased morbidity.DiscussionTreatment for Retroperitoneal Liposarcoma involves R0 resection. In cases where the tumor invades into a nearby organ, it is necessary to weigh the benefit of free margin resection against the adversity of medical...
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionIntrathoracic LPS is a rare tumor. Recurrence is higher with dedifferentiated histology forms. Radical surgery with excision of margins is the primary recommended treatment.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Inhibition of HIF-1α restrains fracture healing via regulation of autophagy in a rat model. Exp Ther Med. 2019 Mar;17(3):1884-1890 Authors: Qiao J, Huang J, Zhou M, Cao G, Shen H Abstract It has been demonstrated that bone fracture is associated with the activation of autophagy, and upregulation of autophagy could promote fracture healing. Previous study by our group demonstrated that activating the HIF-1α pathway via administration of cobalt (II) chloride (CoCl2) could promote fracture healing in vivo. However, the role of hypoxia-inducible factor-1α (HIF-1α) in autophagy remai...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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