Low levothyroxine doses during childhood linked to transient congenital hypothyroidism

A study inThyroid suggests that children given a lower dose of levothyroxine were more likely to develop transient congenital hypothyroidism, compared to those on a higher dose.Healio
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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ConclusionPatients with recurrent aphthous stomatitis were associated with increased risk of specific comorbidities. Physicians should screen for these comorbidities for early detection and treatment.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
Authors: Hirooka M, Ochi H, Hiraoka A, Koizumi Y, Matsuura B, Joko K, Michitaka K, Abe M, Hiasa Y Abstract Hypothyroidism is a frequently occurring complication in patients on lenvatinib treatment. However, little is known about lenvatinib-induced thyrotoxicosis and destructive thyroiditis. We herein report the cases of three patients who developed hyperthyroidism during the course of lenvatinib treatment. All patients had multiple hepatocellular carcinoma of Child-Pugh class A. Two patients required beta blockers for the management of palpitations. One patient developed hyperthyroidism only one week after the init...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
This report describes an association between anorexia nervosa and idiopathic anaphylaxis. While eating disorders affect 0.6% of the population1, and idiopathic anaphylaxis occurs in approximately 1 in 10,000 individuals2 an association between anorexia nervosa and mast cell dysfunction has not previously been described. Features of anorexia nervosa include restriction of eating and energy intake, intense fear of gaining weight, and distorted perception of body weight and shape.1 We describe a fourteen-year-old girl with a history of well controlled hypothyroidism who developed sudden lip and eyelid edema, abdominal pain, s...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
Conditions:   Subclinical hypothyroïdism;   Pregnancy Loss Intervention:   Drug: Thyroxine Sponsor:   Hawler Medical University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
A 37-year-old man of Syrian descent was referred to our nephrology service because of kidney function impairment (estimated glomerular filtration rate  = 38 ml/min per 1.73 m2 Chronic Kidney Disease Epidemiology Collaboration) of unknown origin. Previously the patient was admitted to the orthopedic ward for surgical therapy of pseudarthrosis after multiple lower extremity fractures from inadequate trauma (Figure 1, pseudarthrosis of the right fe mur), occurring first at the age of 13 years. His medical history also included hypothyroidism.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Nephrology Image Source Type: research
CONCLUSIONS: Elevated TgAb levels are associated with symptom burden in HT patients, suggesting a role of thyroid autoimmunity in clinical manifestations of HT. Based on these results, we recommend screening for TgAb antibodies in HT patients with symptom burden. We also suggest that further work on understandings of symptoms appearance due to their autoimmune or hypothyroid causation is needed. PMID: 30332318 [PubMed - as supplied by publisher]
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Publication date: January–February 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 13, Issue 1Author(s): Sedigheh Nouhjah, Hajieh Shahbazian, Seyed Mahmoud Latifi, Reza Azizi Malamiri, Niloofar GhodratiAbstractAimsChild growth is one of the important health indicators in pediatric care. Few studies focused on the impact of prenatal exposure to gestational diabetes mellitus (GDM) on growth trajectories particular in early years of childhood. The aim of this study was identifying growth pattern of GDM exposed offspring's, comparison with new WHO child growth standards.Methods and ma...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Discussion: In the majority of cases, OCA in Caucasians is caused by mutations in the tyrosinase gene. The tyrosinase peptide is normally expressed on the surface of melanocytes, although recent studies have shown its presence in thyroid follicular epithelial cells of patients with Hashimoto ’s thyroiditis. Therefore, although the mechanism is unclear, the present case report may suggest a pathogenetic link between OCA and Hashimoto’s thyroiditis.Eur Thyroid J
Source: European Thyroid Journal - Category: Endocrinology Source Type: research
In this study, we evaluated the factors associated with diffuse uptake by comparing Hashimoto’s thyroiditis patients with or without diffuse uptake in the thyroid.MethodsA retrospective study was conducted of 18 patients with Hashimoto ’s thyroiditis who underwent blood tests, thyroid ultrasonography, and FDG-PET during the period from 2014 to 2015. The patients were divided into two groups: one with diffuse thyroid uptake (group 1,n = 13) and one without diffuse thyroid uptake (group 2,n = 5). Clinical and laboratory parameters, including maximum standardized uptake in the thyroid (...
Source: Thyroid Research - Category: Endocrinology Source Type: research
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