Preoperative Selection and Optimization for Liver Resection in Colorectal Cancer Liver Metastases

AbstractPurpose of ReviewColorectal cancer is the third most common cancer in incidence and the leading cause of death among males and females. Colorectal cancer liver metastatic disease (CRCLM) is the most common cause of death in these patients. Liver resection is the best treatment modality to be offered for CRCLM patients; however, most patients are not good candidates for liver resection. The scope of this review is to discuss the preoperative selection process and the optimization methods that can be used to maximize the eligibility for liver resection in CRCLM.Recent FindingsThe advancement in perioperative management and the engagement of the multidisciplinary methodology in treating patients with colorectal liver metastasis resulted in improving the survival rates, decreasing perioperative complications, and expanding the criteria for liver resection for CRCLM patients.SummaryThe management of colorectal cancer liver metastasis is evolving. Patient selection and perioperative optimization play an essential role to offer a safer liver resection with a reasonable oncologic outcome; personalization of therapy is the next evolution in treating CRCLM patients.
Source: Current Colorectal Cancer Reports - Category: Cancer & Oncology Source Type: research

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Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
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Source: Health Policy and Technology - Category: Health Management Source Type: research
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Source: Bosnian Journal of Basic Medical Sciences - Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research
Condition:   Colorectal Cancer Metastatic Intervention:   Drug: Oxaliplatin Sponsors:   Criterium, Inc.;   Amgen Not yet recruiting
Source: - Category: Research Source Type: clinical trials
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Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Tags: PET Clin Source Type: research
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Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
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Source: Cellular and Molecular Biology Letters - Category: Biochemistry Authors: Tags: Cell Mol Biol Lett Source Type: research
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Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
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Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research
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