Conjugation of phthalocyanine photosensitizer with poly(amidoamine) dendrimer: improved solubility, disaggregation and photoactivity against HepG2 cells.

Conclusion：The conjugation of phthalocyanine photosensitizer ZnPcC4 to polyamidoamine dendrimer G3-PAMAM-NH2 officiously improved the PDT outcomes, in which the optimized binding ratio of ZnPcC4 to G3-PAMAM-NH2 was 6:1. PMID: 29984658 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29984658?dopt=Abstract

Source: Current Cancer Drug Targets - July 6, 2018 Category: Cancer & Oncology Authors: Jiang Z, Ye J, Yang J, Wang J, Jia L, Hoc RJ Tags: Curr Cancer Drug Targets Source Type: research