Treatment of Fistula-in-ano With OTSC® Proctology Clip Device: Short-term Results

ConclusionsThe treatment of anal fistulae with the OTSC® device is a safe sphincter-saving technique in the short term.ResumenIntroducciónEl tratamiento de la fístula anal con el dispositivo OTSC®(over-the-scope-clip) consiste en la inserción de un clip de una aleación elástica denominado Nitinol que ejerce una presión constante sobre el orificio fistuloso interno y facilita el cierre de la fístula. El objetivo de este estudio es analizar los resultados a corto plazo de esta técnica en una serie de casos.MétodosAnálisis retrospectivo de una serie de casos intervenidos de cierre de fístula anal entre junio de 2015 y marzo de 2017 tratados en una unidad especializada con el dispositivo OTSC®. Se incluyeron pacientes con fístulas anales simples y complejas, tratadas previamente o sin tratamientos previos, de origen criptoglandular o por enfermedad de Crohn estable. Se consideró fracaso de la técnica a la supuración anal o complicaciones relacionadas con la inserción del clip.ResultadosSe intervino a 10 pacientes con fístula anal con una mediana de edad de 54 años (rango: 41-70 años). Nueve fístulas fueron de origen criptoglandular y una por enfermedad de Crohn controlada. Tres pacientes presentaron fístulas simples y siete, complejas. El 80% de los pacientes habían presentado cirugías anales previas...
Source: Cirugia Espanola - Category: Surgery Source Type: research

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ConclusionFissurectomy with posterior midline internal sphincterotomy and mucosal anoplasty is safe with minimal complications. It is still a dependable alternative treatment for chronic posterior anal fissures. The fear of keyhole deformity can be well addressed with the added anoplasty.
Source: Current Medicine Research and Practice - Category: General Medicine Source Type: research
Abstract Inflammatory bowel diseases (IBD), Crohn`s disease and ulcerative colitis, are chronic conditions associated with high morbidity and healthcare costs. The natural history of IBD is variable and marked by alternating periods of flare and remission. Even though the use of newer therapeutic targets has been associated with higher rates of mucosal healing, a great proportion of IBD patients remain symptomatic despite effective control of inflammation. These symptoms may include but not limited to abdominal pain, dyspepsia, diarrhea, urgency, fecal incontinence, constipation or bloating. In this setting, commo...
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
Perianal diseases, common complications of Crohn's disease, are difficult to diagnose/manage. Patients with perianal Crohn's disease suffer from persistent pain and drainage, recurrent perianal sepsis, impaired quality of life, and financial burden. Conventional medical and surgical therapies carry risk of infection, myelosuppression, incontinence, disease recurrence. Although the phenotype of Crohn's disease has been extensively studied, reported outcomes are inconsistent. Endoanal ultrasonography is also becoming popular because of low cost and ability to acquire images in real time. Emerging management strategies for tr...
Source: Gastrointestinal Endoscopy Clinics of North America - Category: Gastroenterology Authors: Source Type: research
CONCLUSION: Ulcerative colitis presented a high frequency of intestinal symptoms, and Crohn ’ s disease showed a high frequency of systemic manifestations at the onset of manifestation. There was a long delay in diagnosis, but individuals with more extensive disease and more obvious symptoms showed a shorter delay.RESUMO CONTEXTO: O diagn óstico da doença inflamatória intestinal é frequentemente retardado pela falta de capacidade para reconhecer as suas principais manifestações clínicas. OBJETIVO: Nosso estudo teve como objetivo descrever as manifestações...
Source: Arquivos de Gastroenterologia - Category: Gastroenterology Source Type: research
Conclusions The treatment of anal fistulae with the OTSC® device is a safe sphincter-saving technique in the short term.
Source: Cirugia Espanola - Category: Surgery Source Type: research
Summary BackgroundPatient reported outcomes regarding perianal disease and faecal incontinence in the community‐based inflammatory bowel disease population are poorly described. AimsTo determine the impacts of perianal disease and faecal incontinence on quality of life and employment in inflammatory bowel disease patients. MethodsFor this cross‐sectional study, a comprehensive survey was sent out to members of the Dutch National Crohn's and Colitis patient organisation. Validated questionnaires regarding faecal incontinence and active perianal disease were used to estimate its prevalence's. The effect on the quality of...
Source: Alimentary Pharmacology and Therapeutics - Category: Drugs & Pharmacology Authors: Tags: ORIGINAL ARTICLE Source Type: research
CONCLUSIONS: The treatment of anal fistulae with the OTSC® device is a safe sphincter-saving technique in the short term. PMID: 29525123 [PubMed - as supplied by publisher]
Source: Cirugia eEspanola - Category: Surgery Authors: Tags: Cir Esp Source Type: research
Abstract Microscopic colitis is a chronic inflammatory disease that traditionally affects the large intestine. It is characterized by frequent episodic non‐bloody watery diarrhea. Occasionally, microscopic colitis may present with abdominal pain, fecal incontinence and weight loss.
Source: Journal of Digestive Diseases - Category: Gastroenterology Authors: Tags: Case report Source Type: research
In this month’s issue of Gastroenterology, Molendijk et al1 present their article entitled “Allogeneic Bone Marrow-derived Mesenchymal Stromal Cells Promote Healing of Refractory Perianal Fistulas in Patients with Crohn's Disease.” The authors present a potential new treatment option: mesenchymal stem/stromal cells (MSCs) for patients with refractory perianal Crohn’s disease (CD). Perianal fistulas are a common manifestation of CD affecting about 25% of patients2 and are a particularly destructive and morbid complication that frequently causes purulent drainage, pain, and sometimes fecal incontinence.
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: Editorial Source Type: research
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