Impacts of recolonizing gray wolves (Canis lupus) on survival and mortality in two sympatric ungulates
Canadian Journal of Zoology,Volume 96, Issue 7, Page 760-768, July 2018. There is growing recognition that humans may mediate the strength and nature of the ecological effects of large predators. We took advantage of ongoing gray wolf (Canis lupus Linnaeus, 1758) recolonization in Washington, USA, to contrast adult survival rates and sources of mortality for mule deer (Odocoileus hemionus (Rafinesque, 1817)) and white-tailed deer (Odocoileus virginianus (Zimmermann, 1780)) in areas with and without wolf packs in a managed landscape dominated by multiple human uses. We tested the hypothesis that the addition of wolves to the existing predator guild would augment predator-induced mortality rates for both ungulates. Source of mortality data from adult mule deer and white-tailed deer, respectively, revealed that wolf-related mortality was low compared with that inflicted by other predators or humans. Predator-caused mortality was largely confined to winter. There was little effect of wolf presence on adult deer mortality rates, and there was no difference in mortality between the two deer species relative to wolf-free or wolf-occupied sites. Although this study occurred early in wolf recovery in Washington, our results differ from those demonstrated for gray wolves in protected areas. Thus, we encourage further investigation of effects of direct predation by recolonizing large carnivores on prey in human-dominated landscapes.
Glucocorticoids (GCs) are commonly used to treat systemic lupus erythematosus (SLE). Unfortunately, excessive GCs can induce many side effects associated with disordered fatty acid (FA) metabolism. Although an increased level of total FA has been found after GCs treatment, it is not clear whether all FA species increased or only certain FA species were altered. A gas chromatography–mass spectrometry-based FA profiling approach was performed to reveal the alterations of FA species in SLE model mice (MRL/lpr) after treatment with 5 mg/kg of prednisone. The study showed a distinct FA profile in MRL/lpr mice compared to ...
Title: Sticking With Meds Lowers Lupus Patients' Diabetes RiskCategory: Health NewsCreated: 2/21/2020 12:00:00 AMLast Editorial Review: 2/24/2020 12:00:00 AM
CONCLUSIONS: The 2019 EULAR/ACR criteria for SLE had comparable performance to the 2012 SLICC criteria regarding diagnostic sensitivity and specificity in Korean population of SLE and other rheumatic diseases. However, the new criteria could not reach higher specificity than the 2012 SLICC criteria. PMID: 32083550 [PubMed - as supplied by publisher]
CONCLUSIONS: Male gender, exposure to high cumulative doses of prednisone, family history of early arterial vascular disease and occurrence of previous arterial thrombosis are independent risk predictors of arterial vascular events in patients with systemic lupus erythematosus. Abnormal ABI may be related to high risk for arterial vascular events. PMID: 32083548 [PubMed - as supplied by publisher]
CONCLUSIONS: Testing for autoantibodies against both Ro peptides may aim diagnosis, classify clinical manifestations in disease entities and define prognosis in certain autoimmune disorders. A distinct weight could be given to the isolated anti-Ro specificities in the SS classification criteria. PMID: 32083547 [PubMed - as supplied by publisher]
Authors: Ceccarelli F, Orefice V, Perrone G, Pirone C, Perricone C, Truglia S, Miranda F, Pacucci VA, Spinelli FR, Galoppi P, Alessandri C, Valesini G, Conti F Abstract OBJECTIVES: We evaluated age at natural menopause and the prevalence of premature ovarian failure (POF) in a monocentric Caucasian cohort of patients with systemic lupus erythematosus (SLE). METHODS: In this cross-sectional study, we enrolled women affected by SLE compared with healthy controls (HC) to investigate data about natural menopause (amenorrhoea for at least 12 months at ≥40 years) and POF (amenorrhoea for at least 12 months at
This study is to systematically evaluate the association of serum/plasma HCY levels in SLE. A search was done using PubMed, Embase, Web of Science, and ScienceDirect databases up to 7 April 2019. Thirty-six articles including 2919 SLE patients and 3120 healthy controls were finally included in this meta-analysis. The HCY levels were significantly higher in SLE patients than in healthy controls (P
In this study, the outer membrane from E. coli was isolated and used to produce OM particles with a diameter of approximately 100 nm. These prepared OM particles were applied in a thermophoretic immunoassay. First, outer membrane (OM) particles with lipopolysaccharides (LPS) and anti-LPS antibodies were used as a model to demonstrate proof of concept and the difference in E. coli thermophoresis was explained by the changes in the molecular surface area (A) and effective charge (σeff). The hydrodynamic size of the molecules was measured as a changing parameter, molecular surface area (A), by dynamic laser scattering...
Corrigendum to "Association between Serum Matrix Metalloproteinase- (MMP-) 3 Levels and Systemic Lupus Erythematosus: A Meta-Analysis". Dis Markers. 2020;2020:5943216 Authors: Lee JM, Kronbichler A, Park SJ, Kim SH, Han KH, Kang HG, Ha IS, Cheong HI, Kim KH, Kim G, Kim DS, Chae HW, Lee CH, Lee KH, Shin JI Abstract [This corrects the article DOI: 10.1155/2019/9796735.]. PMID: 32082435 [PubMed - in process]
Systemic lupus erythematous (SLE) disproportionately impacts patients of color and socioeconomically disadvantaged patients. Similar disparities in HIV were reduced through a World Health Organization-endorsed...