Serum lipoproteins are not associated with the severity of asthma

ConclusionsThe current findings confirm a role of LDL as a potential biomarker in the diagnostic process for asthma, and suggest that LDL cannot be used as marker of severity of the disease.
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research

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Publication date: Available online 23 August 2019Source: The LancetAuthor(s): Jo Hardy, Christina Baggott, James Fingleton, Helen K Reddel, Robert J Hancox, Matire Harwood, Andrew Corin, Jenny Sparks, Daniela Hall, Doñah Sabbagh, Saras Mane, Alexandra Vohlidkova, John Martindale, Mathew Williams, Philippa Shirtcliffe, Mark Holliday, Mark Weatherall, Richard Beasley, Andrew Corin, Liz DronfieldSummaryBackgroundIn adults with mild asthma, a combination of an inhaled corticosteroid with a fast-onset long-acting β-agonist (LABA) used as reliever monotherapy reduces severe exacerbations compared with short-acting &b...
Source: The Lancet - Category: General Medicine Source Type: research
Publication date: Available online 23 August 2019Source: The LancetAuthor(s): Marc Gauthier, Sally E Wenzel
Source: The Lancet - Category: General Medicine Source Type: research
Conclusions: Children with obesity received more oral steroid prescriptions than those at a healthy weight, which may be indicative of worse asthma control. We did not observe significant ethnic disparities. PMID: 31437069 [PubMed - as supplied by publisher]
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
This report describes the prevalence of SHS exposure among nonsmoking youth in 2013-2016, as defined by serum cotinine, a metabolite of nicotine. PMID: 31442196 [PubMed - in process]
Source: NCHS data brief - Category: American Health Tags: NCHS Data Brief Source Type: research
Historically, pediatric allergic diseases have been understudied, and their treatments were missing their mark. For example, not very many decades ago “parentectomy” was a viable therapeutic option when treating severe pediatric asthma. Subsequently, the concept of asthma as an inflammatory disease emerged, and we began using inhaled corticosteroids (ICS) with the thought that using them regularly would interrupt disease progression and even r everse underlying asthma. To prove this, in the early 1990s, the National Institutes of Health initiated the CAMP (“Child Asthma Management Program”) study, b...
Source: Immunology and Allergy Clinics of North America - Category: Allergy & Immunology Authors: Tags: Foreword Source Type: research
Authors: Ito A, Ishiguro T, Takaku Y, Kagiyama N, Kamei K, Takayanagi N Abstract A 42-year-old man with asthma presented in 2007 with chest infiltration and productive cough. Pycnoporus sanguineus and Perenniporia tephropora were repeatedly isolated from sputum and bronchial washing fluids. Because we lacked immunologic evidence, we could not diagnose him with allergic bronchopulmonary mycosis (ABPM) due to these basidiomycetous fungi. At that time, serum-specific IgE and IgG against Schizophyllum commune findings were negative. Inhaled beclomethasone/salmeterol improved his condition. Seven years later, mucous plu...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
AbstractAsthma is one of the most common chronic health conditions in children, and social determinants are thought to be important risk factors. We used Georgia data from the Behavioral Risk Factors Surveillance Survey (BRFSS), and data from the Georgia hospital and emergency department survey for children with a diagnosis of asthma. All data were from the years 2011 to 2016. SAS and SUDAAN were used to calculate weighted prevalence estimates and to perform univariate and multivariate analysis of the association between social determinants, demographic characteristics, other potential risk factors, and asthma-related outc...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
AbstractTo study variables associated with Emergency Department (ED) utilization among pediatric patients with asthma in a Federally Qualified Health Center (FQHC). We analyzed Electronic Health Record (EHR) data in a retrospective cohort study of patients with asthma between ages 2 and 18 who received primary care at a FQHC. The primary outcome studied was a visit to the ED at Ann and Robert Lurie ’s Children’s Hospital (LCH) for an acute visit related to asthma. Univariate analyses and a multiple logistic regression were performed to study the effect of demographic and clinical variables on ED utilization. Of...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
Study in African - American children shows symptom - based adjustment of inhaled corticosteroids is feasible
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Family Medicine, Pediatrics, Pharmacy, Pulmonology, Allergy, Emergency Medicine, Journal, Source Type: news
We report about a case of a compassionate off-label use of the anti-interleukin-5-agent mepolizumab in a ventilated patient with life-threatening asthma attack in eosinophilic asthma. The patient suffered from severe eosinophilic asthma and was transmitted to our hospital with an asthma attack and a life-threatening respiratory state under ventilation. Since high dose steroids had not yielded a sufficient respiratory improvement mepolizumab was administered subcutaneously. After administration of mepolizumab respiratory state and ventilation parameter improved significantly. Two days after administration the patient was we...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
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