Non contrast versus contrast enhanced MRI of the great thoracic vessels in pediatric congenital heart disease: A quantitative and qualitative analysis

Publication date: Available online 19 June 2018Source: The Egyptian Journal of Radiology and Nuclear MedicineAuthor(s): Wessam Abdelrahman Elzayat, Marwa M. Onsy, Mohamed Talaat Ali, Hassan Ali El-Kiki, Rania Ali HegazyAbstractAimTo compare 3D steady-state free-precession (SSFP) non-contrast magnetic resonance angiography (NC-MRA) with contrast-enhanced MRA (CE-MRA) for quantitative and qualitative analysis of thoracic arteries in pediatric patients with congenital heart disease.MethodologyForty patients with thoracic vascular anomalies (22 boys &18 girls) ranging in age between 6 months and 14 years (mean age 4.58 ± 4.5) were included in this prospective study. Measurements of the thoracic arteries were taken by 3D SSFP NC-MRA &CE-MRA. Image quality was assessed using a four-point score. Pearson's and Spearman's Correlation Coefficients were calculated for correlation analysis while Student's t and Mann-Whitney U tests were used for comparative analysis, Bland-Altman plots were employed to demonstrate the level of agreement between the 2 techniques.ResultsMeasurements from NC-CMRA images were comparable to those from CE-MRA. All measures highly correlated (r > 0.9), 3D SSFP NC-MRA exhibited a significantly higher image quality score than contrast- enhanced MRA, the mean difference was significantly lower than that of the 3D SSFP; (p-value
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research

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Condition:   Coronary Artery Disease Interventions:   Diagnostic Test: CT angiography;   Diagnostic Test: Invasive coronary angiography Sponsors:   Johns Hopkins University;   Canon Medical Systems Recruiting
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