Infertile men are more likely to develop prostate cancer

Researchers  from Lund University, Sweden, found men who are unable to have children naturally or via IVF are overall 47 per cent more likely to develop the life-threatening condition.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Authors: Anderson RC, Newton CL, Anderson RA, Millar RP Abstract The gonadotropin receptors, luteinising hormone receptor, and follicle-stimulating hormone receptor, play a central role in governing reproductive competency/fertility. Gonadotropin hormone analogues have been utilised clinically for decades, in assisted reproductive therapies, and in the treatment of various infertility disorders. While these treatments are effective, the clinical protocols demand multiple injections, and the hormone preparations can lack uniformity and stability. The past two decades have seen a drive to develop chimeric and modifie...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
Researchers  from Lund University, Sweden, found men who are unable to have children naturally or via IVF are overall 47 per cent more likely to develop the life-threatening condition.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
AbstractPurpose of ReviewNon-standard shift work schedules negatively impact the overall health of shift workers, and several studies have shown that shift work, specifically, is detrimental to urogenital health. The aims of this study are to systematically review the literature and determine the effect of shift work on the outcomes of hypogonadism, male infertility, lower urinary tract symptoms, and urogenital cancers.Recent FindingsRecent evidence supports associations between non-standard shift work and an increase in the frequency of prostate cancer and the severity of erectile dysfunction, lower urinary tract symptoms...
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research
Women having trouble getting pregnant sometimes try yoga, meditation or mindfulness, and some research suggests that psychological stress may affect infertility. But what about men: Does their mental state affect a couple's ability to conceive? The latest research on this subject was published Thursday in the journal Fertility and Sterility and suggests that a link between mental health […]Related:CDC comes close to an all-clear on romaine lettuce as E. coli outbreak nears historic levelSurrogate mothers ask Supreme Court to stop ‘exploitation’ of women and babiesMore men with low-risk pro...
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news
Women having trouble getting pregnant sometimes try yoga, meditation or mindfulness, and some research suggests that psychological stress may affect infertility. But what about men: Does their mental state affect a couple's ability to conceive? The latest research on this subject was published Thursday in the journal Fertility and Sterility and suggests that a link between mental health […]Related:CDC comes close to an all-clear on romaine lettuce as E. coli outbreak nears historic levelSurrogate mothers ask Supreme Court to stop ‘exploitation’ of women and babiesMore men with low-risk pro...
Source: Washington Post: To Your Health - Category: Consumer Health News Source Type: news
Abstract Selenium is an essential trace element, the deficiency of which leads to the development of several serious diseases, including male infertility, prostate cancer, etc. It has been shown that oxidative stress contributes to the progression of prostate cancer, and antioxidants such as selenium and vitamin E can significantly reduce the risk of this disease. Sodium selenite, one of the selenium compounds that induce the formation of reactive oxygen species, is considered as a potential anticancer agent. The SS concentrations that lead to a decrease in the viability of human prostate adenocarcinoma cells (lin...
Source: Molekuliarnaia Biologiia - Category: Molecular Biology Authors: Tags: Mol Biol (Mosk) Source Type: research
CONCLUSIONS: Male infertility is a proxy of the overall male health status. Physicians should comprehensively assessed men presenting for couple infertility and properly followed-up these patients given their higher risk of developing cancer. PMID: 29595040 [PubMed - as supplied by publisher]
Source: Minerva Urologica e Nefrologica - Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Associations between male infertility and cancer are gaining clinical attention. Relationships between infertility and cancer have traditionally been studied in women, but recent work has focused on the male component of reproduction. Infertile men are at an elevated risk to develop various malignancies later in life, primarily genitourinary malignancies such as testicular and prostate cancer. Rates of testicular and high-grade prostate cancer in infertile men appear to be at least double the risk in the general population.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Views and reviews Source Type: research
Huixiao Hong Endocrine disrupting chemicals (EDCs) can mimic natural hormone to interact with receptors in the endocrine system and thus disrupt the functions of the endocrine system, raising concerns on the public health. In addition to disruption of the endocrine system, some EDCs have been found associated with many diseases such as breast cancer, prostate cancer, infertility, asthma, stroke, Alzheimer’s disease, obesity, and diabetes mellitus. EDCs that binding androgen receptor have been reported associated with diabetes mellitus in in vitro, animal, and clinical studies. In this review, we summarize the st...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
This study provided a more comprehensive description of the seminal exosomes proteome and could also be a resource for further screening of biomarkers and comparative proteomics studies, including those associated with male infertility and prostate cancer.
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research
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